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mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif";} </style> <![endif]--><!--[if gte mso 9]><xml> <o:shapedefaults v:ext="edit" spidmax="1026"/> </xml><![endif]--><!--[if gte mso 9]><xml> <o:shapelayout v:ext="edit"> <o:idmap v:ext="edit" data="1"/> </o:shapelayout></xml><![endif]--></head> <body style="" color="#AAAAFF" alink="black" bgcolor="white" lang="EN-US" link="blue" vlink="purple"> <div class="WordSection1"> <div class="MsoNormal" style="text-align: center;" align="center"><span style=""> <hr align="center" size="2" width="100%"> </span></div><br><div class="MsoNormal" style="text-align: center;" align="center"><span style=""> <hr align="center" size="2" width="100%"> </span></div> <h1 style="text-align: center;" align="center"><span style="color: darkblue;">Genetic Association Course<o:p></o:p></span></h1> <h2 style="text-align: center;" align="center"><span style="color: darkblue;">July 23-27, 2012<br> Max <span class="SpellE">Delbrck</span> Center (MDC) for Molecular Medicine<br> Berlin, Germany<o:p></o:p></span></h2> <div class="MsoNormal" style="text-align: center;" align="center"><span style=""> <hr align="center" size="2" width="100%"> </span></div> <p><span style="font-size: 13.5pt;">The Third Annual Berlin Genetic Association Course will be held at the <a href="http://www.mdc-berlin.de/" target="extern">MDC</a> in Berlin from July 23-27, 2012. The goal of the course is to teach the course participants both theory and application of methods for population based association analysis, with a concentration on the analysis of whole genome scan data. <o:p></o:p></span></p> <p><span style="font-size: 13.5pt;">The cost of the 5 day course is 975 EUR for researchers from an academic institution, and 1,950 EUR for individuals from private (for profit) companies. This fee covers tuition, Monday evening wine and cheese party and course related expenses (handouts, etc.) but not room, board or meals. Inexpensive housing is available for course participants at the MDC and nearby hotels. <o:p></o:p></span></p> <p><span style="font-size: 13.5pt;">The maximum number of participants is 30. Emphasis in this course is on strategies for genetic mapping of complex human traits. It will include theory as well as practical exercises. The exercises will be carried out using a variety of computer programs (PLINK, <span class="SpellE">GenABEL</span>, MACH, UNPHASED, EIGENSTRAT and R, etc.) and with pencil and paper. The emphasis of this course is analysis of population based whole genome data including genotype and sequence data.<span style="">&nbsp; </span>TOPICS include: Association analysis of qualitative and quantitative traits; single marker and haplotype analysis; analysis of whole genome association study data; complex trait rare variant association analysis of next generation sequence data; data quality control for genotype and next generation sequence data; haplotype reconstruction; <span class="SpellE">tagSNP</span> selection; controlling population admixture (genomic<span style="">&nbsp; </span>control, principal components analysis, <span class="SpellE">etc</span>); imputing genotype data; detecting gene x gene and gene x environmental interactions; power and sample size estimation for both genotype and rare variant data; permutation (estimating empirical p-values); and false discovery rate (FDR). The organizers and instructors for the course are <a href="http://www.bcm.edu/genetics/facultyaz/leal.html">Suzanne Leal</a> (Baylor College of Medicine) and <a href="http://capella.uni-kiel.de/enter.htm">Michael <span class="SpellE">Nothnagel</span></a> (Kiel University &amp; Max <span class="SpellE">Delbrck</span> Center).<o:p></o:p></span></p><p><span style="font-size: 13.5pt;"><span style=""></span><o:p></o:p></span></p> <p><span style="font-size: 13.5pt;">For additional information on the Genetic Association Analysis Course please contact <a href="mailto:sleal@bcm.edu?subject=genetic%20association%20analysis%20course%202009">Suzanne Leal</a>: <o:p></o:p></span></p> <ul type="disc"> <li class="MsoNormal" style=""><span style="font-size: 13.5pt;">email: <a href="mailto:sleal@bcm.tmc.edu?subject=GMC%202007%20Berlin">sleal@bcm.tmc.edu</a> <o:p></o:p></span></li> <li class="MsoNormal" style=""><span style="font-size: 13.5pt;">Tel: +1 (713) 798-4011 <o:p></o:p></span></li> <li class="MsoNormal" style=""><span style="font-size: 13.5pt;">Fax: +1 (713) 798-4373 <o:p></o:p></span></li> </ul> <p><b style=""><u><span style="font-size: 13.5pt;"><a href="http://www.jurgott.org/suzanne2012-07-23/schedule.htm">Click here for course schedule</a><o:p></o:p></span></u></b></p><p><b style=""><span style="font-size: 13.5pt; color: rgb(0, 176, 80);"><a href="http://www.jurgott.org/suzanne2012-07-23/GenABELexercise.pdf"><span style="color: rgb(0, 176, 80);">Click here for <span class="SpellE">GenAbel</span> Exercise on Population Substructure/Admixture</span></a><o:p></o:p></span></b></p> <p><b style=""><span style="font-size: 13.5pt; color: rgb(0, 176, 80);"><a href="http://www.jurgott.org/suzanne2012-07-23/multitest_answers_5.pdf"><span style="color: rgb(0, 176, 80);">Click here for <span class="SpellE">Multitest</span> Answers<o:p></o:p></span></a></span></b></p> <p><b><span style="font-size: 13.5pt;"><a href="http://www.mdc-berlin.de/en/about_the_mdc/wegweiser/How_to_find_us/index.html">Click here for maps and directions to the MDC</a></span></b><span class="MsoHyperlink"><o:p></o:p></span></p> <p><span style="font-size: 13.5pt;"><a href="http://www.bbb-berlin.de/e_gasthaus.html"><b>Click here for the information on MDC Housing</b></a></span></p> <p><b><span style="font-size: 13.5pt;"><a href="http://tourist.visitberlin.de/en">Click here for Berlin tourist information</a><o:p></o:p></span></b></p> <p><b style=""><span style="font-size: 13.5pt;"><a href="http://capella.uni-kiel.de/gmc2011.assoc/gac2011.htm">Click here for photos and datasets from the Genetic Association Course, Berlin, <span class="GramE">July</span> 2011</a><o:p></o:p></span></b></p> <p><b style=""><span style="font-size: 13.5pt;"><a href="http://capella.uni-kiel.de/gmc2011.linkage/gmc2011.htm">Click here for photos from the Basic Gene Mapping Course, Berlin, <span class="GramE">November</span> 2011</a></span></b><span class="MsoHyperlink"><o:p></o:p></span></p> <p><b style=""><span style="font-size: 13.5pt;"><a href="http://capella.uni-kiel.de/gmc2010.assoc/gac2010.htm">Click here for photos and datasets from the Genetic Association Course, Berlin, <span class="GramE">May</span> 2010</a></span><span class="MsoHyperlink"><o:p></o:p></span></b></p> <p><b style=""><span style="font-size: 13.5pt;"><a href="http://capella.uni-kiel.de/gmc2010.linkage/gmc2010.htm">Click here for photos from the Basic Gene Mapping Course, Berlin, <span class="GramE">October</span> 2010</a></span></b><span class="MsoHyperlink"><o:p></o:p></span></p> <p><b style=""><span style="font-size: 13.5pt;"><a href="http://capella.uni-kiel.de/gmc2009/gmc2009.htm">Click here for photos from the Basic Gene Mapping Course, Berlin, <span class="GramE">November</span> 2009</a><o:p></o:p></span></b></p> <p><b><span style="font-size: 13.5pt;"><a href="http://capella.uni-kiel.de/gmc2008/gmc2008.htm">Click here for photos from the Basic Gene Mapping Course, Berlin, <span class="GramE">July</span> 2008</a></span></b><span class="MsoHyperlink"><o:p></o:p></span></p> <p><b><u><span style="font-size: 13.5pt; color: blue;"><a href="http://capella.uni-kiel.de/gmc2007/gmc2007.htm">Click here for photos from the Basic Gene Mapping Course, Berlin, <span class="GramE">July</span> 2007</a></span></u></b></p> <p><a href="http://capella.uni-kiel.de/gmc2006/gmc2006.htm"><b><span style="font-size: 13.5pt;">Click here for photos from the Basic Gene Mapping Course, Berlin, <span class="GramE">July</span> 2006</span></b></a></p> <p><a href="http://capella.uni-kiel.de/gmc2005/gmc2005.htm"><b><span style="font-size: 13.5pt;">Click here for photos from the Basic Gene Mapping Course, Berlin, <span class="GramE">July</span> 2005</span></b></a></p> <p><a href="http://capella.uni-kiel.de/gmc2004/gmc2004.htm"><b><span style="font-size: 13.5pt;">Click here for photos from the Basic Gene Mapping Course, Berlin, <span class="GramE">July</span> 2004</span></b></a></p> <p><a href="http://capella.uni-kiel.de/gmc2003/gmc2003.htm"><b><span style="font-size: 13.5pt;">Click here for photos from the Basic Gene Mapping Course, Berlin, <span class="GramE">July</span> 2003</span></b></a></p> <p>&nbsp;</p> </div> </body></html>